The story of the discovery of penicillin by Alexander Fleming is well-known. On returning from a holiday on September 3, 1928, he remarks that in a petri dish with a bacterial culture (staphylococci) there is an area without any bacterial … Read more
Thought that genetic modification (gene transfer) was artificial? Just done by human researchers? New research now reveals that gene transfer is quite a common event even among higher plants. And even among species quite far apart. Particularly among species that … Read more
The title of our last episode (Pride comes before a fall) may not do justice to the major importance of the sulfas for the further development of medicinal chemistry. In fact, the sulfas mark the start of a new era … Read more
At present, most seaweed is grown in Asia. But the North Sea, between England and the European continent, is an attractive location for growing seaweed. This sea is rich in nutrients. Seaweed can be processed to food, useful substances and … Read more
Both the UK and the US greet M&B 693 or sulfapyridine with much enthusiasm. In the war years, this message about the sulfas is a much-needed piece of good news. Project ‘100 years of antibiotics’ Episode 9. In the crossfire … Read more
The art of forest gardening will eventually produce what we might call an ‘edible forest’. Highly valued because of its biodiversity, ecological resilience and the productivity of its biomass. Forest gardens need little maintenance and are climate resistant. An alternative … Read more
In 1937 already, the medical profession in the United Kingdom, France and the United States recognizes the major importance of the sulfanilamide and the other sulfas; for different reasons in each country. Project ‘100 years of antibiotics’ Episode 8. The … Read more
Ten years ago, last month, a tsunami struck the West coast of Japan. It flooded the Fukushima nuclear reactor. This resulted in a partial meltdown and a hydrogen explosion, that released a lot of radioactivity. The media devoted many articles … Read more
We haven’t yet told the whole story about the sulfas in Germany during WW II. For further reading we recommend the book by John E. Lesch, already referred to: The First Miracle Drugs, How the sulfa drugs transformed medicine. In … Read more
After Prontosil, the sulfas make a breakthrough. The success really takes off in WW II, in particular in the forces of Germany and its allies. But the success has a major black rim. IG Farben is not just a major … Read more
We need to move through the energy transition fast. Because continuous carbon dioxide emissions will result in unacceptable climate changes. That’s why we need transition paths that meet with little resistance. The Scientific American recently proposed a pathway in which … Read more
According to one version of the history of Aspirin, German chemist Felix Hoffmann who works with Bayer, has it all sorted out in 1897. Felix is 29 years old. As the story goes, his father suffers from arthritis and after … Read more
In a report released last month, Lux Research looked into CO2 utilization. The company forecasts a growth in this sector to $ 70 billion by 2030 and to $ 550 billion by 2040. CO2 will be put to good use … Read more
In the column ‘There is no such thing as an individual’ we mentioned the influence of the microorganisms in our bodies on our development. But biologists have already gone much further along this path. Our microbiome, the living guests in … Read more
The success of Salvarsan leads Paul Ehrlich to believe that he will quickly be able to eliminate many other pathogens. In 1914, he addresses the 7th International Medical Congress in London. In paraphrase he says: ‘All countries in the world … Read more
Wooden windows? Wood, not for the frame but for the transparent part, instead of glass? Yes, modern research has shown that we can make transparent wood with a relatively benign chemical treatment. A new application for this biobased material! Windows … Read more
Many of our readers will know the prominent role played by Germany in the development and the many applications of synthetic dyes. They will also know the name of Justus von Liebig, the ‘founding father’ of coal tar research. This … Read more
‘The chemicals and materials industry is going to see more dramatic change over the next 20 years than it has in at least the last 50,’ says Anthony Schiavo, Senior Analyst at Lux Research. They just completed a report on … Read more
Costs of producing renewable energy keep coming down; and technologies for cheap energy storage keep evolving. Therefore, the eternal problems with solar and wind energy appear to be more and more outdated (‘what to do if the sun doesn’t shine … Read more
For those living in the 19th century, it was by no means evident that we could use chemistry as a weapon against bacteria. Chemistry was a young science. It found its applications in polluting and dangerous industries. The mere idea … Read more
In 1913, Hugh Hampton Young returns to the US from the international medical conference in London, deeply impressed by Paul Ehrlich’s chemotherapy. Young works as a surgeon at the Brady urological institute of Johns Hopkins University in Baltimore. Following Ehrlich’s … Read more
The most important low-carbon energy sources, renewables and nuclear, compete for investment funds. But if we are not mistaken, the dice have already been thrown in this contest of renewables versus nuclear. Renewables have won. Although it might still take … Read more
A recent article in Nature Energy confirms what we might have surmised already: renewable sources are much better at creating a low-carbon energy future than nuclear power. They do need quite another electricity infrastructure. But grid companies quickly learn how … Read more
In 1890, Robert Koch appoints Paul Ehrlich his assistant. Although Ehrlich (1854-1915) is above all a medical doctor (together with Emil Adolf von Behring he develops a vaccine against diphtheria), he is primarily fascinated by chemistry. Project ‘100 years of … Read more
In long-term conflicts, often we can hardly tell when they started, or what their origin was. And who played what part? Often, the beholder is the judge of the answer; or the latter depends on the moment of reflection on … Read more
As soon as World War I had ended, research on infections soared. There was pressure to come up with results, much pressure. Bacterial infections had been responsible for most casualties in the muddy trenches. In the previous decades, researchers had … Read more
In a small clinical study conducted in April and May 2020, British scientists investigated the effect of inhalation of nebulised interferon-beta-1a (SNG001) on the development of COVID-19 in patients. The results are encouraging and justify further research. Lung infections Being … Read more
New biobased materials pop up everywhere these days. On the basis of organic materials, often processed with modern chemical technologies. They seem to be able to substitute many fossil-based and mineral materials. Just a few of these innovations. Natural materials … Read more
Animal tests are a controversial issue. On the one hand, many people object to actions that deliberately damage animal welfare. On the other hand, we need these tests in order to establish the safety of medicines and new materials; people … Read more
Our lifestyle greatly promotes the outbreak of pandemics like Covid-19, and this could have devastating consequences. Unless we take action. Says a new report by IPBES, the Intergovernmental Platform on Biodiversity and Ecosystem Services. Policy measures are required. An era … Read more
Modern biologists are waging a fierce debate on the meaning of the concept of the individual. Definitions of well-known phenomena like symbiosis and parasitism need to be rephrased. The debate goes beyond the world of plants and micro-organisms; the subject … Read more
Plastic recycling has become a hot topic. The seriousness of plastic pollution has forced itself upon us. Industry, indeed the world, needs to close the plastic loop. But we don’t know how yet. Industry and policy makers will have to … Read more
Suddenly, articles on plastic recycling pop up everywhere. Spurred on the one hand by continued growth in plastics production; and on the other hand by the ever growing problem of plastic waste. Scientists foresee that in 2050, there will be … Read more
A revolution has taken place in the construction industry: the development of mass timber, the technical term for industrial timber. It allows for the construction of innovative buildings. Mass timber as a construction material can now even outperform bricks, concrete … Read more
The world is rediscovering timber. Thanks to new technologies that open up new constructive techniques; and to a better appreciation of sustainability. MaterialDistrict, a Dutch foundation, has published Tomorrow’s timber, a book that explores all aspects of building with it, … Read more
Since 2011, the Caribbean is bothered by seaweed. Large quantities of Sargassum are washed up on the shores. There it rots, depleting the coastal waters from oxygen, releasing hydrogen sulphide and methane. And trapping marine life, coral reefs and fish. … Read more
Plant biostimulation is a new approach to agriculture. So far, substances that assisted the farmer were fertilizers and plant protection products, each with a well-known chemical composition. Biostimulants on the other hand are mixtures of compounds and organisms defined primarily … Read more
All over the world, antibiotics resistance increases. Overdose prescriptions are an important cause. And also the natural phenomenon of increasing resistance as the same medicine is being used for years at a stretch. The problem is severe in humane antibiotics … Read more
The effects are well-known. After an evening with just a little too much wine consumption, you wake up with a headache. Not because of the alcohol but because of the sulphite in the wine. Sulphite is an antioxidant, a necessary … Read more
In Europe, most people seem to have lost their belief in improvement. A concept of dreamers. But improvement takes place all the time; and the odd thing about this is that many improvements are swift and fundamental in nature, but … Read more
The solutions are here!, talking about major global problems. Solutions that exist already but are not generally applied. Or that are under severe and undeserved attack and therefore receive insufficient support. We have in mind: renewable energy and energy storage, … Read more
Researchers at Monash University in Melbourne, Australia, have developed a new technology for drinking-water production. They use metal-organic frameworks (MOFs) that remove ions dissolved in salt or brackish water, producing potable water. The MOFs can be regenerated quickly, under the … Read more
This book is what a review should be all about: lengthy (365 pg), thorough, several tables and hundreds of references. Overall, this is a complete book on a highly relevant topic. Biostimulants: natural substances supporting vegetative growth, uptake of nutrients, … Read more
Mankind has known leather for about seven thousand years, now. Leather is durable and versatile. And biodegradable. But it is produced as a by-product of the meat industry, in a process with much environmental pollution. So here’s the good news … Read more
The Dutch Wadden islands aimed to attain energy autarky in 2020. They fail to reach that target. For in order to do this, energy production and consumption don’t just need to match over a year; they also need to match … Read more
The European Academies’ Science Advisory Council (EASAC) urges the European Commission to base its carbon accounting on science and the real effects on climate. The present accounting rules favour energy from biomass. Whereas often, burning biomass doesn’t lower CO2 emissions … Read more
Battery recycling is an area long neglected by battery producers. Performance and cost were much more important. So now we are stuck with a rapidly growing heap of worn-out batteries of which we don’t know how to treat it. Or … Read more
Much excitement in the universe of battery technology. Battery storage is rapidly growing world-wide, important for the energy transition. Batteries are improving and their costs are falling, all the time. And the million-mile battery might be coming soon. Meaning that … Read more
‘Biobased materials and chemicals are driven by performance,’ we wrote in 2016. They do not compete primarily on cost, but on the new functionalities they offer. Now, in the middle of record low oil prices, this principle receives support from … Read more
Food loss and waste currently causes an estimated $1 trillion in economic losses globally each year, according to Lux Research, a Boston-based tech and advisory company. This constitutes not just an economic crisis but also a major humanitarian one. It … Read more