{"id":24182,"date":"2023-01-21T16:07:56","date_gmt":"2023-01-21T15:07:56","guid":{"rendered":"https:\/\/www.biobasedpress.eu\/?p=24182"},"modified":"2023-01-21T16:36:58","modified_gmt":"2023-01-21T15:36:58","slug":"cats-claw-als-veelbelovend-plantaardig-antibioticum","status":"publish","type":"post","link":"https:\/\/www.biobasedpress.eu\/nl\/2023\/01\/cats-claw-als-veelbelovend-plantaardig-antibioticum\/","title":{"rendered":"Cat&#8217;s claw als veelbelovend plantaardig antibioticum"},"content":{"rendered":"<p><strong>Bacteri\u00eble <a href=\"https:\/\/www.biobasedpress.eu\/nl\/2020\/10\/resistentie-tegen-antibiotica-en-hoe-die-te-overwinnen\/\">resistentie<\/a> tegen antibiotica blijft toenemen en wordt algemeen erkend als een dreigend probleem. Er wordt daarom veel onderzoek gedaan naar alternatieven. E\u00e9n van de veelbelovende middelen is cat\u2019s claw. Deze plant uit het regenwoud is uitzonderlijk rijk aan fytochemicali\u00ebn. Wat is cat\u2019s claw precies en wat zijn de mogelijke toepassingen?<\/strong><\/p>\n<figure id=\"attachment_24175\" aria-describedby=\"caption-attachment-24175\" style=\"width: 260px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_flowers_Yamuna01_Wikimedia_Commons.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-24175\" src=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_flowers_Yamuna01_Wikimedia_Commons.jpg\" alt=\"cat's claw\" width=\"270\" height=\"360\" \/><\/a><figcaption id=\"caption-attachment-24175\" class=\"wp-caption-text\">Bloemen van cat\u2019s claw. Yamuna01, Wikimedia Commons.<\/figcaption><\/figure>\n<h2><strong>Wat is cat\u2019s claw?<\/strong><\/h2>\n<p>Cat\u2019s claw ofwel kattenklauw (Uncaria tomentosa) is een doornige klimplant uit het Amazonewoud van Peru, Bolivia en Brazili\u00eb. Onder de bevolking staat de plant bekend als u\u00f1a de gato. Hij kan tot 30 centimeter dik en 30 tot 100 meter hoog worden.<\/p>\n<p>De plant dankt zijn naam aan de klauwachtige doornen die aan de stam groeien, waarmee hij zich aan bomen en struiken vasthoudt. De inheemse bevolking van Zuid- en Midden-Amerika gebruikt schors, bast en wortels al duizenden jaren als middel bij infecties en chronische ontstekingen.<\/p>\n<h2><strong>Waardoor interessant als geneesplant?<\/strong><\/h2>\n<p>Sinds de jaren negentig van de vorige eeuw wordt cat\u2019s claw door de Wereldgezondheidsorganisatie (WHO) al erkend als geneeskrachtige plant. Vooral het gebruik bij koorts, darmproblemen, artrose, artritis en andere ontstekingen is bekend.<\/p>\n<figure id=\"attachment_24177\" aria-describedby=\"caption-attachment-24177\" style=\"width: 270px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_Yamuna01_Wikimedia_Commons.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-24177\" src=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_Yamuna01_Wikimedia_Commons.jpg\" alt=\"cat's claw\" width=\"280\" height=\"210\" \/><\/a><figcaption id=\"caption-attachment-24177\" class=\"wp-caption-text\">Cat\u2019s claw. Yamuna01. Wikimedia Commons.<\/figcaption><\/figure>\n<p>Cat\u2019s claw werkt verzachtend, celbeschermend, ontstekingsremmend en immunomodulerend. Hoewel veel van het onderzoek naar Cat&#8217;s claw gericht is op de antioxiderende en ontstekingsremmende eigenschappen, begint meer onderzoek zich te richten op het antimicrobi\u00eble potentieel van de plant.<\/p>\n<p>Uit onderzoek blijkt inmiddels dat de stoffen in cat\u2019s claw op zichzelf of in samenwerking met antibiotica een antibacterieel potentieel hebben. Ook hebben ze een schimmelwerend en antiparasitair effect.<\/p>\n<p>Onderzoek van dr. Zhang en collega&#8217;s toont aan dat cat&#8217;s claw effectief is bij de behandeling van groeiende en persisterende vormen van Borrelia burgdorferi, de veroorzaker van de ziekte van Lyme. Uit een ander onderzoek blijkt de antivirale activiteit van cat\u2019s claw tegen het Dengue-virus. Cat\u2019s claw is ook effectief gebleken tegen Enterococcus faecalis, Staphylococcus aureus en Candida albicans. Onderzoeken naar de antimicrobi\u00eble activiteit van cat\u2019s claw tegen Micrococcus flavus en Bacillus subtilis zijn eveneens veelbelovend, al is de activiteit tegen deze microben wel zwakker dan die van reguliere antibiotica.<\/p>\n<h2><strong>Hoe werkt cat\u2019s claw?<\/strong><\/h2>\n<p>Het effect cat\u2019s claw zou vooral komen van indool- en oxindoolalkalo\u00efden, polyfenolen en terpeno\u00efden. Met deze overwegend giftige stoffen beschermt de plant zich mogelijk tegen de aanvallen van schimmels, virussen en bacteri\u00ebn in het vochtige tropische woud.<\/p>\n<figure id=\"attachment_24179\" aria-describedby=\"caption-attachment-24179\" style=\"width: 285px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_Uncaria_tormentosa_foto_Renata-Harrison_Wikimedia_Commons.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-24179\" src=\"https:\/\/www.biobasedpress.eu\/wp-content\/uploads\/2023\/01\/Cats_claw_Uncaria_tormentosa_foto_Renata-Harrison_Wikimedia_Commons.jpg\" alt=\"cat's claw\" width=\"295\" height=\"197\" \/><\/a><figcaption id=\"caption-attachment-24179\" class=\"wp-caption-text\">Cat&#8217;s claw (Uncaria tormentosa). Foto: Renata Harrison, Wikimedia Commons.<\/figcaption><\/figure>\n<h2><strong>Heeft het middel bijwerkingen?<\/strong><\/h2>\n<p>De hoge niveaus van tannines in kattenklauw kunnen bij grote hoeveelheden leiden tot misselijkheid, maagklachten en diarree. In zeldzame gevallen kan cat\u2019s claw een lage bloeddruk veroorzaken, evenals een verhoogd risico op bloedingen en zenuwschade. Ook zijn er gevallen bekend van anti-oestrogene effecten en een nadelige invloed op de nieren.<\/p>\n<p>De tetracyclische oxindole alkalo\u00efden in de bast kunnen het effect van andere alkalo\u00efden omkeren en maagbloedingen veroorzaken door het antistollingseffect. Daarom zijn deze stoffen verwijderd uit de meest gebruikte middelen die cat\u2019s claw bevatten.<\/p>\n<h2><strong>Voor wie is cat\u2019s claw niet geschikt?<\/strong><\/h2>\n<p>Door de milde contraceptieve werking wordt aan vrouwen met een kinderwens geadviseerd om geen cat\u2019s claw te nemen. Hetzelfde geldt voor vrouwen die borstvoeding geven, al is dit vooral vanwege een gebrek aan informatie.<\/p>\n<p>Ook mensen met de volgende aandoeningen dienen cat\u2019s claw te vermijden:<br \/>\n&#8211; Bloedingsstoornissen<br \/>\n&#8211; Auto-immuunziekte<br \/>\n&#8211; Nierziekte<br \/>\n&#8211; Leukemie<br \/>\n&#8211; Problemen met de bloeddruk<br \/>\nIedereen die in afwachting is van een operatie dient eveneens het gebruik van cat\u2019s claw te staken aangezien het middel bloedverdunnend kan werken.<\/p>\n<h2><strong>Interacties met medicijnen<\/strong><\/h2>\n<p>Cat\u2019s claw kan interfereren met sommige medicijnen, zoals die voor bloeddruk, cholesterol, kanker en bloedstolling. Om die reden zou iedereen die deze middelen gebruikt, eerst moeten overleggen met een arts voordat hij cat\u2019s claw gaat gebruiken.<\/p>\n<p>Meer informatie over natuurlijke middelen en hun werking is te vinden in <a href=\"https:\/\/www.nutribites.nl\/kennisbank\/\">Nutribites kennisbank<\/a>.<\/p>\n<p><em>Bronnen<br \/>\n<\/em>Blanck, J.J. et al. (2022). Comprehensive Review of the Components in Cat\u2019s Claw (Uncaria tomentosa) and Their Antibacterial Activity. AppliedChem, 2(1), 1-29.<br \/>\nWhitmire, K. (2020). Potential Antimicrobial Activity of Cat\u2019s Claw in the Management of Persistent Lyme Disease. Clinical Applications for Scientific Innovation.<br \/>\nErowele, G.I. et al. (2009). Pharmacology and therapeutic uses of cat\u2019s claw. American journal of health-system pharmacy, 66(11), 992-5.<br \/>\nStyczynski, J. et al. (2006). Alternative medicine remedies might stimulate viability of leukemic cells. Pediatric blood and cancer, 46(1), 94-8.<br \/>\nTabassum, N. (2011). Role of natural herbs in the treatment of hypertension. Pharmacognosy reviews, 5(9), 30\u201340.<br \/>\nHilepo, J.N. et al. (1997). Acute renal failure caused by &#8216;cat&#8217;s claw&#8217; herbal remedy in a patient with systemic lupus erythematosus. Nephron, 77(3), 361.<br \/>\nFlythe, J.E. et al. (2009). Silicate nephrolithiasis after ingestion of supplements containing silica dioxide. American journal of kidney diseases, 54(1), 127-30.<br \/>\nVogel, J.H.K. et al. (2005). Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and Integrative Medicine). Journal of the American College of Cardiology, 46(1), 184-221.<\/p>\n<p><em>Ineterssant? Lees dan ook:<br \/>\n<\/em><a href=\"https:\/\/www.biobasedpress.eu\/nl\/2020\/10\/resistentie-tegen-antibiotica-en-hoe-die-te-overwinnen\/\">Resistentie tegen antibiotica, en hoe die te overwinnen<\/a><br \/>\n<a href=\"https:\/\/www.biobasedpress.eu\/nl\/2022\/02\/chemie-versus-bacterie-54-als-chemie-en-biotech-samen-optrekken\/\">Chemie versus bacterie, # 54. Als chemie en biotech samen optrekken<\/a><br \/>\n<a href=\"https:\/\/www.biobasedpress.eu\/nl\/2022\/01\/chemie-versus-bacterie-47-de-bedreigingen-in-de-21ste-eeuw-resistentie\/\">Chemie versus bacterie, # 47. De bedreigingen in de 21ste eeuw<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bacteri\u00eble resistentie tegen antibiotica blijft toenemen en wordt algemeen erkend als een dreigend probleem. Er wordt daarom veel onderzoek gedaan naar alternatieven. E\u00e9n van de veelbelovende middelen is cat\u2019s claw. &#8230; <a title=\"Cat&#8217;s claw als veelbelovend plantaardig antibioticum\" class=\"read-more\" href=\"https:\/\/www.biobasedpress.eu\/nl\/2023\/01\/cats-claw-als-veelbelovend-plantaardig-antibioticum\/\" aria-label=\"Lees meer over Cat&#8217;s claw als veelbelovend plantaardig antibioticum\">Lees verder<\/a><\/p>\n","protected":false},"author":4,"featured_media":24175,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[249],"tags":[24,126,271,131],"class_list":["post-24182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-groene-grondstoffen","tag-biochemicalien","tag-gewassen","tag-medicijnen","tag-onderzoek"],"yoast_head":"<title>Cat&#039;s claw als veelbelovend plantaardig antibioticum - Bio Based Press<\/title>\n<meta name=\"description\" content=\"Cat&#039;s claw (kattenklauw) is een plant uit het Amazonegebied met sterke medicinale werkingen. 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